Clarkson et al. found that one bout of strenuous eccentric exercises resulted in rapid adaptation of muscle strength and active ROM that can be seen within 5 days of the initial bout. They found that the damage created by the eccentrics is repairable, part of the adaptation process, and that the adaptation was producible with less stressful bouts. They also found that the adaptation rate varied from person to person as measurements were taken days, weeks, and months after the initial bout and the responses were varied, but consistently increased. Her conclusion is that it is likely that cellular and neurological factors can influence a person’s rate of adaptation. This supports our notion that clients will have varying rates of adaptation based on a number of factors while also revealing that eccentric exercises are the most effective way to create range and strength adaptations. An exercise program which works to identify a person’s readiness for stress and likely adaptation rate, prior to loading tissue, would be prudent and necessary in order to minimize the possibility of the eccentrics’ damage adversely affecting the client’s immune system and inflammation markers.